ARACHNE

ARACHNE is designed to model spiking networks of neurons and astrocytes. It is equipped with optimised parallel algorithms for remote computations and a user-friendly interface. A neuroscientist without IT background should be able to incorporate a wide variety of biophysical mechanisms pertinent to nerve and astroglial cells, within a single network model.

ARACHNE enables an investigator to build and explore cellular networks of arbitrary biophysical and architectural complexity using the logic of NEURON and a simple interface on a local computer. The operator can exercise online control over an optimized computational kernel installed on an AMAZON cluster. The network design can combine neuronal (wired) and astroglial (extracellular volume-transmitted) connections and adopt realistic cell models from NEURON library.

Installation

There are 2 versions of ARACHNE. Each version has its own method of installation:

1. “Web installation” is a self-installing version of ARACHNE for local (host) and remote (cloud) computations.

   • ARACHNE Download the Arachne installer for Windows.
   • The self-installing version can be downloaded after registration.
   • OS : Windows 7, 10 or 11.
   • Fast internet connection.
     
     

2. “Basic installation” is a source code installation of ARACHNE

   • The source code and the user manual can be downloaded at: ZIP file ARACHNE
   • Source code of ARACHNE includes 4 versions: Demo, Full, Matlab and Mobile.
   • Computer languages: MatLab, C++ and NEURON.
   • OS : Windows 7/10/11, Linux or Android.
   • Fast internet connection.

Basic configurations

A set of basic parameter configurations of ARACHNE and detailed descriptions of control results the user can find in PLOS Comp Biology paper

Documentation

Manual and API documentation can be found in User Guide PDF